I am a Ph.D. student in the Department of Computational Medicine and Bioinformatics (DCMB) at the University of Michigan. I have concluded my undergraduate academic endeavors at Sun Yat-sen University with a B.S. degree, majoring in Pharmaceutical Sciences. Subsequently, I obtained my M.Phil. degree from The Chinese University of Hong Kong. In my leisure time, I enjoy playing bridge and sports.

News

• March 2024, I completed the rotation and joined in Alexey Nesvizhskii’s lab. 🚀
• February 2024, ProNet DB is accepted by Database! 🧨
• January 2024, SSBlazer is accepted by Genome Biology! 🎉
• September 2023, begin Ph.D. study at DCMB, University of Michigan.

Publication

(*equal contribution, #corresponding)

• ProNet DB: A proteome-wise database for protein surface property representations and RNA-binding profiles
  Junkang Wei*, Jin Xiao, Siyuan Chen, Licheng Zong, Xin Gao, Yu Li. Database, 2024.
  [Paper][Server][Code]

• SSBlazer: A genome-wide nucleotide-resolution model for predicting single-strand break sites
  Sheng Xu*, Junkang Wei*#, Siqi Sun, Jizhou Zhang, Ting-Fung Chan, Yu Li#. Genome Biology, 2024.
  [Paper][Server][Code]

• Long-read PacBio genome sequencing of four environmental saprophytic Sporothrix species spanning the pathogenic clade
  Weian Du, Domenico Giosa, Junkang Wei*, Letterio Giuffrè, Ge Shi, …, BMC Genomics, 2022.
  [Paper]

• Low-dose AAV-CRISPR-mediated liver-specific knock-in restored hemostasis in neonatal hemophilia B mice with subtle antibody response
  Xiangjun He, Zhenjie Zhang, Junyi Xue, Yaofeng Wang, Siqi Zhang, Junkang Wei, …, Nature Communications, 2022.
  [Paper]

• Identification of a binding site on soluble RANKL that can be targeted to inhibit soluble RANK-RANKL interactions and treat osteoporosis
  Dane Huang, Chao Zhao, Ruyue Li, Bingyi Chen, Yuting Zhang, Zhejun Sun, Junkang Wei, …, Nature Communications, 2022.
  [Paper]

• Structure-based discovery and structural basis of a novel broad-spectrum natural product against the main protease of coronavirus
  Yuting Zhang, Hongxia Gao, Xiaohui Hu, Qisheng Wang, Fanglin Zhong, Xuelan Zhou, Cheng Lin, Yang Yang, Junkang Wei, …, Journal of Virology, 2022.
  [Paper]

• Protein–RNA interaction prediction with deep learning: structure matters
  Junkang Wei*, Siyuan Chen, Licheng Zong, Xin Gao, Yu Li, Briefings in Bioinformatics, 2022.
  [Paper]

• DGAT-onco: A differential analysis method to detect oncogenes by integrating functional information of mutations
  H Zhang, J Wei, Z Liu, X Liu, Y Chong, Y Lu, H Zhao, Y Yang. IEEE International Conference on Bioinformatics and Biomedicine, 2021.
  [Paper]

• Discovery of new LXRβ agonists as glioblastoma inhibitors
  Hao Chen, Ziyang Chen, Zizhen Zhang, Yali Li, Shushu Zhang, Fuqiang Jiang, Junkang Wei, …, European Journal of Medicinal Chemistry, 2020.
  [Paper]

• Discovery of tissue selective liver X receptor agonists for the treatment of atherosclerosis without causing hepatic lipogenesis
  Chanjuan Li, Hao Chen, Xinying Chen, Yanwen Li, Pei Hua, Junkang Wei, …, European Journal of Medicinal Chemistry, 2019.
  [Paper]

• Chemical constituents from Daphne tangutica and their cytotoxicity against nasopharyngeal carcinoma cells
  Zhiong Yin, Yanfang Cheng, Junkang Wei, Xiangkun Luo, …, Fitoterapia, 2018.
  [Paper]

Last update: Apr 2024